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Read Living on the Edge by Jani Laukkanen free ebook with 2 easy steps and start reading right away.Role of antibodies directed to a synthetic peptide in active systemic lupus erythematosus.
Active systemic lupus erythematosus (SLE) is characterized by the presence of anti-DNA antibodies, and the immunopathological role of these autoantibodies is not fully understood. We have synthesized several synthetic peptides (fused to glutathione-S-transferase), and obtained rabbit antisera directed to each of these peptides. Among these antibodies, an antibody directed to the peptide 50% homologous to the human DNase I high-activity peptide II (50%, d50%) was found to cause thymocyte loss in mixed lymphocyte cultures at high concentrations. As the 50% homologous peptide is located in the enzyme’s active site, the binding of antibodies to this peptide may inhibit the interaction between the DNase I-peptide II complex and the T cell receptor. In this study, we analyzed clinical and laboratory findings in 13 patients with SLE, and found that the percentages of CD3+ cells and the ratios of CD4+/CD8+ cells in peripheral blood mononuclear cells were significantly higher in patients with anti-50% d50% antibody than in those with anti-d50% and anti-d100% (peptide 20%) antibodies. The clinical course of the disease in patients with anti-50% d50% antibody was significantly different from that in patients with other antibodies. These findings suggest that the anti-50% d50% antibody may be involved in the development of active SLE.Q:

Python: Pickling last class in a namespace

Is there any way of pickingling a class when that class is in a namespace?
I have a class that represents the result of a query:
…
class QueryResult(object):
def __init__(self, *

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