Nowi Tropiciele. E Nauczyciela. Multibook. Klasa 1

Nowi Tropiciele. E Nauczyciela. Multibook. Klasa 1

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Nowi Tropiciele. E Nauczyciela. Multibook. Klasa 1
Nowi Tropiciele. E Nauczyciela. Multibook. Klasa 1
.Human leukocyte antigen antibodies, transplant organ damage, and morbidity in renal-transplanted patients.
The presence of human leukocyte antigen antibodies (HLA Abs) plays an important role in renal transplant rejection. Although the mechanisms of HLA Abs-related organ damage are still poorly understood, these agents have been associated with (i) thrombotic microangiopathy, (ii) complement-dependent cytotoxicity, (iii) antibody-mediated rejection, (iv) glomerulonephritis, and (v) graft vasculopathy. HLA Abs have been also associated with chronic graft damage including primary glomerulonephritis and intimal arteriolar inflammation. The progression of acute transplant rejection to the chronic damage is often complicated by the presence of HLA Abs. In fact, HLA Abs can act as antigens stimulating the recipient’s immune system contributing to the failure of the transplanted organ. Their presence and the humoral immune response against these agents may be associated with increasing numbers of infections, deaths, and graft loss. Therefore, it is important to identify HLA Abs and understand their pathogenic role and their clinical impact. Management of HLA Abs in renal transplant patients may also be relevant and useful to prevent these events. In this review, HLA Abs, the clinical syndromes that HLA Abs play a role in, and the current knowledge on management of HLA Abs with a special focus on the clinical impact of HLA Abs is discussed.Title

Author

Date of Award

1-1-1984

Document Type

Dissertation

Degree Name

Doctor of Philosophy (PhD)

Major

Department

History

First Advisor

John Holliday

Abstract

What can we know about the social structures of early America and the cultures of the nation’s original inhabitants? Why did the first Indian nations negotiate or make war or hold “peace congresses?” And who were the Indian leaders, warrior or civilian? This study takes a social history approach to investigate these questions. Sociological, economic and family history information is examined to attempt to define and describe the Indian nations’ structures, for the purpose of comparison with those of other western societies.

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