Insemnarile Unei Pustoaice Download 34 |VERIFIED|

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Insemnarile Unei Pustoaice Download 34

The apolipoprotein B-100 epsilon4 allele is protective for the development of schizophrenia in a Japanese population.
Apolipoprotein E (APOE) is a major lipid carrier protein that affects lipoprotein metabolism and cholesterol homeostasis. Previous studies have suggested that APOE may be a candidate gene for schizophrenia. To investigate the association between APOE polymorphism and schizophrenia in the Japanese population, a family-based association study was conducted using 221 clinically diagnosed probands, with and without schizophrenia, and their first-degree relatives. Transmission disequilibrium test (TDT) suggested that the epsilon4 allele of the APOE gene was significantly under-transmitted to the proband (P=0.026) and the unaffected offspring (P=0.001) of the schizophrenia probands, but was not associated with schizophrenia in the unaffected offspring of schizophrenia probands (P=0.138). However, both TDT-P and TDT-U did not support the association between the epsilon4 allele and schizophrenia. The lack of an association between the epsilon4 allele and schizophrenia may be influenced by the smaller sample size of this study compared with previous studies.Newsgroups: rec.org.amiga
Path: cantaloupe.srv.cs.cmu.edu!ridic.org!tor-news.at!magnesium.interhop.com!uunet!inXS.sprint.net!nntp.primenet.com!lupin.buz.st-and.ac.uk!tsjaq
From: tsjaq@lupin.buz.st-and.ac.uk (Tim Small)
Subject: Re: Update 5.1
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Sender: news@lupin.buz.st-and.ac.uk (USENET Newsmaster)
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Organization: University of St Andrews, Scotland
References:
Date: Thu, 06 Apr 1993

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Insemnarile Unei Pustoaice Download 34 |VERIFIED|

Insemnarile Unei Pustoaice Download 34 |VERIFIED|

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