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Category:DriversWednesday, March 5, 2011
Ghost Light Cuts Short GHOSTLIGHT German release to be updated in Q4 2011
GHOSTLIGHT was always meant to be released in Germany, not the US. Ryan Taylor, CTO of Headlight, sees no value in funding the consumer and retail version of the Ghostlight plugin, and will concentrate on the German language version in the future. Ryan goes on to say that the German version will be updated regularly. In fact, he is currently working on a new Ghostlight adding new features and new languages. You can follow Ryan and Headlight at www.headlightgaming.comRole of Src tyrosine kinase in cell migration induced by endostatin/endostatin receptor.
The anti-angiogenic inhibitor, endostatin/endostatin receptor (ES/ESR), inhibits tumor cell migration through angiostatin/angiostatin receptor (Kupfer-Reuter et al., 1999. FEBS Lett. 460, 221-4). In this study, ES/ESR induced tumor cell migration in a dose-dependent manner. ES/ESR-mediated cell migration was associated with activation of the Src family kinase (SFK) and with phosphorylation of FAK, paxillin and p130CAS. The Src family inhibitor PP2 inhibited ES/ESR-mediated cell migration. Furthermore, there was also an increase in the phosphorylation of SFK and activation of paxillin and p130CAS in an ES/ESR dose-dependent manner. Overexpression of Src or its substrate p130CAS in the cells inhibited Src and p130CAS activities in ES/ESR stimulated cells. These findings suggest that ES/ESR activates SFK, which results in tumor cell migration through the tyrosine phosphorylation of FAK, paxillin and p130CAS. https://overmarket.pl/?p=18469
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